Bacopin®
and Gingko work very differently to improve memory
and restore and maintain mental functioning and memory.
Both work differently and yet very synergistically to provide
something very unique. This is a comprehensive formula supporting
memory alertness, cognition and nerve health. Bacopin®
is a standardized extract from Bacopa monniera (20% Bacosides
A&B) that improves the synaptic brain function, bacosides
help repair damaged neurons by adding muscle to kinase,
the protein involved in the synthesis of new neurons to
replace the old ones. Depleted synaptic activity is thus
restored, leading to boosting of memory, while reducing
anxiety in stressed individuals. Gingko biloba extract (24%/6%)
is recognized for improving blood flow to the brain, providing
antioxidant protection, and improving mental alertness.
Rounding out the formula is Phosphytidylcholine, Phosphytidylserine,
DHA and Acetyl-L-Carnitine providing additional essential
known nutrients for brain function and health. Ginger and
Bioperine® aid absorption.
1.
Bacopin®
Bacopin®
is an extract from Bacopa monniera standardized to a minimum
of 20% total bacosides (A&B). The traditional name for
Bacopa monniera is "Brahmi". Traditional application
suggests that Bacopin® has a direct effect
on improving brain functions, increasing concentration,
and in promoting memory functions. Bacosides are believed
to play a protective role in the synaptic functions of the
nerves in the hippocampus, the seat of memory. Nerve impulses
are transmitted across the synapses and their degeneration
is believed to contribute to impaired memory and cognition.
Clinical studies performed in India confirm that the bacosides
can revitalize intellectual functions in children and reduce
anxiety in stressed individuals, thereby contributing to
improved brain functions1,2.
1. Sharma, R. et al. (1987)
J. Res. Edu. Ind. Med. 1-10.
2. Singh, R.H., Singh, L.J. (1980) J. Res. Ayur. Siddha.
1:133-148.
2.
Phosphatidylcholine
Phosphatidylcholine is
a phospholipid that is abundant in nerve-cell membranes
and is required for nerve growth and function. Choline,
which is a part of the molecule, is used to produce acetylcholine,
a neurotransmitter important in cognition and memory1. Human
studies also suggest that choline may benefit memory. In
a placebo-controlled study, investigators gave 61 healthy
older adults (aged 50 to 80 years) either phosphatidylcholine-rich
lecithin or a placebo for five weeks. By the end of the
study, memory test scores of the phosphatidylcholine group
improved significantly, exceeding those of the placebo group.
Memory lapses in the treated group also reduced by 48%2.
1. Zeisel, S.H., DaCosta,
K.A., et al. (1991) FASEB J, 5: 2093-98.
2. Safford, F. & Baumel, B. (1994) Research On Social
Work Practice, 4: 349-58,
3.
Ginkgo biloba
Ginkgo biloba has been
used to improve cerebral blood circulation and to protect
the nerves against damaging free radicals. Both these effects
indirectly help in improving mental alertness, awareness
and cognition. People with impaired blood circulation in
the nervous system would therefore be particularly benefited.
Ginkgo biloba thus helps in the maintenance of healthy nerves
and retards degenerative processes1. Several clinical studies
have validated the role of Ginkgo biloba in the management
of dementia2.
1. DeFeudis, F.V. (1991).
Ginkgo biloba Extract (EGb 761): Pharmacological activities
and clinical applications. Elsevier. 13(3): 163- 167.
2. LeBars, P., et al. JAMA, 278(16): 1327-32, Oct. 22/29,1997.
4.
Ginger extract
Ginger (Zingiber officinale)
has been used to promote healthy digestion. Impaired digestion
often hampers mental performance on account of the accompanying
discomfort and sluggish metabolism. Contemporary usage has
shown ginger to be effective in supporting digestive functions1.
The extract is standardized for 5% gingerols, the active
constituents which enhance digestion and metabolism.
1. Yamahara, J. et al. (1985)
J. Ethnopharmacology, 13: 217-225.
5.
Phosphatidylserine
Phosphatidylserine is a
phospholipid that forms one of the large "lipid"
molecules that hold the other large molecules in a cell’s
membrane systems together. The cell membrane plays a vital
role in the entry of nutrients into the cell and phosphatidylserine
helps to attenuate these functions, thereby helping to maintain
the cell’s internal environment and improving the
release of neurotransmitter biochemicals. All these effects
contribute to the protective effect of phosphatidylserine
on the hippocampus, the seat of memory, and in retarding
the loss of connections between the nerves that occurs during
aging1. Recent clinical studies validate the role of phosphatidylserine
in the management of memory loss associated with aging2.
1. Kidd, P.M. (1995) Phosphatidylserine
(PS) a remarkable brain cell nutrient. Lucas Meyer.
2. Cenacchi, T., et al. Aging, 5: 2, 123-33, April 1993.
6.
DHA
Docosahexanoic acid (DHA),
a polyunsaturated fatty acid also known as an omega-3 fatty
acid, has been shown to play a critical role in infant brain
development and vision starting from the fetal development
stage1. Recent research has also linked the rising rate
of moodiness among adults and lack of attention in children
to an imbalance in the ratio of omega-3 fatty acids to omega-6
fatty acids (arachadonic acid)2,3. The inclusion of DHA
in this formulation renders additional support to brain
functions.
1. Urano S (1998) Biofactors,
7 (1-2):103-12.
2. Hibbeln, J., & Salem, N. (1995). Am J Clin Nutr,
62: 1-9.
3. Stevens, L.J., et al. ( 1995).Am J Clin Nutr, 62: 761-68.
7.
Acetyl-L-carnitine
Acetyl-L-carnitine (ALC),
is a nutrient that helps in brain functions by triggering
the release of neurotransmitters, such as acetylcholine.
Acetyl-L-carnitine acts on the central nervous system and
blocks factors that inhibit the release of acetylcholine.
It is therefore helpful in reviving depressed cholinergic
systems, thereby promoting memory and cognition1.
1. Casdorph, H.R., &
Walker, M. Toxic Metal Syndrome: 315. Garden City Park,
NY: Avery Publishing Group, 1995.
8.
Bioperine®
Bioperine®
is a standardized extract obtained from black pepper, containing
not less than 95% piperine. The product is a natural bioavailability
enhancer for nutrients and is proven to improve the uptake
and utilization of several nutritional supplements, including
vitamins, antioxidants and minerals1,2.
