Antioxidant Complex (and other Natural Antioxidants) Curcumin C3 Complex® a patented form provides a 95% curcuminoids extract from turmeric root with a unique blend of three distinct curcuminoids. Curcuminoids are very potent anti-oxidants with specific anti-viral, anti-bacterial, anti-fungal, anti-cancer, and very strong anti-inflammatory action. It supports the liver and has cholesterol lowering effects. Curcumin suppresses COX-2, over-expression of COX-2 is related to the development of chronic inflammatory diseases. This product also has triple action protectant antioxidants that prevent free radical formation and neutralize existing free radicals. The curcuminoids are combined with Vitamin A (as Beta Carotene), Vitamin E and Selenium (as Selenomethionine) all are very well known antioxidant substances in their own right, and is supported by the bio-availability enhancing action of Bioperine® black pepper fruit extract.

1. Curcumin C3 Complex®

Recent research has revealed that free radicals play an important role in the progression of aging and related conditions. Curcumin C3 Complex® , a unique composition of three curcuminoids, is a standardized extract from turmeric, or Curcuma longa. Unlike other antioxidants, there are two particular modes of antioxidant action of curcuminoids. The "prevention mode" prevents the formation of free radicals. The second mechanism, the "intervention mode", neutralizes the already formed free radicals by free radical scavenging. Curcumin C3 Complex® is therefore considered an effective "Bioprotectant" due to its dual activity of prevention and intervention1.

1. Majeed, M. et al. (1995) Curcuminoids : Antioxidant Phytonutrients. NutriScience Publishers Inc., Piscataway, New Jersey.

2. Beta carotene

Beta carotene is a fat soluble carotenoid which is converted in the intestinal wall to Vitamin A. The excess beta carotene performs important antioxidant functions. Beta carotene has been proven to destroy reactive oxygen species generated by ultra violet rays and damaging chemicals, thereby preventing degenerative free radical chain reactions in the body. Clinical studies support the efficacy of beta carotene in preventing oxidative damage to the skin, eyes and lungs1.

1. Jialal, I. and Grundy, S.M. (1992) J. Lipid Research, 33:899-905.

3. Vitamin E

Vitamin E is fat soluble and therefore acts as an antioxidant in cell membranes and other tissues that contain fat. The tocopherols are an effective form of Vitamin E, useful in preventing the oxidation of fats and intervening in the progression of free radical chain reactions. Clinical studies have revealed the role of Vitamin E in supporting heart health1, providing support to immune functions in the elderly2, offering protection to structures of the eye3 4 and retarding the progression of degenerative conditions5.

1. Stampfer, M. et al. (1996) Lancet, 374:781-86.
2. Meydani, S.N. et al. (1997). JAMA 1380-86.
3. Robertson, J. et al. (1991) Am. J. Clin. Nutr. Suppl. 53: 346S-351S.
4. Snodderly, D.M. (1995) Am. J. Clin. Nutr. 62 (6 Suppl):1448S-1461S
5. Bostick, R.M. (1993) Environ. Cancer Research. 53: 4230-37.

4. L-Selenomethionine

L-Selenomethionine is a safe form of supplemental selenium. Selenium is an essential trace element in nutrition for the maintenance of health. Epidemiologic investigations indicate an association between low selenium status and below-optimum cardiovascular function. Selenium is also an effective detoxicant antioxidant due to its role in the glutathione peroxidase detoxification mechanism, which protects cellular components from oxidative stress and damage. Glutathione is involved in the quenching of free radicals and detoxification of certain harmful chemicals. Clinical studies correlate health status and general well being with the blood levels of selenium1.

1. Badmaev, V., Majeed, M. (1996) Alt Therapies, 2 (4):59-65.

5. Bioperine®

Bioperine® is a standardized extract obtained from black pepper, containing not less than 95% piperine. It is a natural bioavailability enhancer for nutrients and is proven to improve the uptake and utilization of several nutritional supplements, including vitamins, antioxidants and minerals1,2.

1. Majeed, M., et al. United States Patent #s. 5,536,506 (1996) and 5,744,161 (1998).
2. Guido, S. et al. (1998). Planta Medica 64: 1-4.

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*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.