Coleus
Forskohlii is the only known natural source of the
unique adenylate cyclase activating phytonutrient, Forskolin.
Adenylate cyclase is the enzyme involved in the production
of Cyclic Adenosine Monophosphate (cAMP), a very important
energy molecule, known as the “second messenger”
which has a positive effect on many biochemical processes
in the body. When cAMP is raised inside the cells, many
physiological and biochemical changes occur, including;
inhibition of platelet activation and degranulation, inhibition
of mast cell degranulation and histamine release, increased
force of heart muscle contraction, relaxation of arteries
and smooth muscle, increased insulin secretion, increased
thyroid function, and increased lipolysis (burning fat for
fuel). Forskolin has also been shown to lower blood pressure,
through its ability to relax arteries and veins. Studies
validate the use of forskolin in maintaining cardiac, circulatory
and respiratory health. Forskolin also effectively increases
lean muscle mass, while burning fat.
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